Acute severe hepatitis outbreak in children: A perfect storm. What do we know, and what questions remain?
During the first half of 2022, the World Health Organization reported an outbreak of acute severe hepatitis of unknown aetiology (AS-Hep-UA) in children, following initial alerts from the United Kingdom (UK) where a cluster of cases was first observed in previously well children aged <6 years.Sporadic cases were then reported across Europe and w